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Sequencing-only on Ultima Sequencers

High-throughput sequencing of customer-prepared libraries on the Ultima platform to support cost-efficient and scalable genomic research.
Pre-made Library Sequencing on Ultima Platforms

Through strategic collaboration with Ultima Genomics, Novogene is proud to be among the first Certified Service Providers (CSPs) for the UG 100 platform. With the UG 100 now fully integrated into our sequencing fleet, Novogene delivers a high-performance, scalable, and cost-efficient pre-made library sequencing solution, optimized for high-throughput research applications.

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Why Choose Novogene for Ultima Sequencing?

Ultra-High Throughput
Ultra-High Throughput

Up to 10 billion reads per wafer for ultra-high data output

Cost-Efficient Sequencing
Cost-Efficient Sequencing

Lower cost per million reads compared to other short-read platforms

Fast Turnaround
Fast Turnaround

Fast turnaround time with streamlined end-to-end workflow support

Optimized Data Delivery
Optimized Data Delivery

More efficient data delivery with CRAM format options

Flexible Library Compatibility
Flexible Library Compatibility

Compatible with both Ultima and Illumina libraries, with a seamless conversion service available

US-Based Processing
US-Based Processing

Local processing and sequencing in the U.S. for faster logistics and compliance

Supported Applications of Ultima platforms

Single-cell sequencing
Single-cell sequencing
RAN sequencing
RAN sequencing
Methylation sequencing
Methylation sequencing
Whole genome sequencing
Whole genome sequencing
Proteomics
Proteomics

Specifications

Service Features

FeaturesUltima Genomics Sequencing
Sequencing PlatformUltima UG100™
Read ConfigurationSingle-End ~300 bp (SE300)
Output per WaferUp to ~8–10 billion reads (application dependent)
Library CompatibilityUltima-compatible library;
Illumina-compatible library (conversion offered)
Data QualityHigh-quality sequencing suitable for a broad range of applications
Data DeliveryCRAM files or simulated paired-end FASTQ files (application dependent)

Project Workflow

With Ultima’s UG100 Solaris platform, Novogene now provides pre-made library wafer sequencing on Ultima with end-to-end support—from sample submission to analysis guidance.

Project Workflow

Resources

How Does It Work?

The UG 100 dramatically reduces sequencing costs by introducing a novel sequencing substrate built on 200-mm silicon wafers, a core material in the electronics industry. Instead of traditional microfluidics, the system uses contactless spin-coating, a manufacturing technique adapted from semiconductor fabrication.


Its sequencing chemistry is largely natural, with only a small fraction of nucleotides labeled with fluorescent tags—significantly reducing reagent complexity and cost.

During each cycle, one nucleotide type (A, C, T, or G) is added across the entire wafer. The surface is then scanned to determine base incorporation. This shifts base calling from identifying which base was added to determining how many were incorporated. The fluorescent labels are subsequently removed using the same spin-coating process.


The system’s high-speed circular motion enables rapid, high-resolution imaging across the full wafer surface.

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All of these innovations deliver not only cost and throughput advantages, but also exceptional data quality. With Ultima Genomics’ novel ppmSeq™ technology, single-nucleotide variants (SNVs) can be detected with one-part-per-million accuracy, setting a new standard for sequencing precision.

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Ready to Start Your Project?

Our platform offers tailored solutions for

your unique experimental needs, ensuring a seamless experience from project design to data delivery.